NASET News Alert

Extent of Developmental Delays Varies with Autism

September 09, 2022

Developmental milestone progress in autism varies substantially under different conditions, according to a study published online July 18 in JAMA Pediatrics. Susan S. Kuo, Ph.D., from the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, and colleagues assessed variability in the age at which autistic individuals attain key developmental milestones. The analysis included 17,098 autistic individuals and 4,145 siblings without an autism diagnosis (ages 4 to 17 years). The researchers found that individuals with autism showed delays in milestone attainment versus their unaffected siblings, with median delays ranging from 0.7 to 19.7 months. The presence of co-occurring intellectual disability, carrying a neurodevelopmental disorder-associated rare genetic variant, and being diagnosed with autism by age 5 years were associated with more severe and more variable delays in autism. Read More