Aicardi Syndrome is a rare genetic disorder identified by the French Neurologist, Dr. Jean Aicardi in 1965. The number of identified cases of girls with Aicardi syndrome is approximately 300 - 500 worldwide. It is characterized by the partial or complete absence of the structure that links the two hemispheres of the brain, the corpus callosum.
The disorder affects only girls. Onset of Aicardi Syndrome generally begins between the ages of 3 and 5 months with infantile spasms, a type of childhood seizure. Symptoms include seizures, mental retardation and lesions on the retina of the eye that are specific to the disorder. Aicardi Syndrome may be associated with other brain defects such as a smaller than average brain and cavities or gaps in the brain filled with cerebrospinal fluid. There is no cure for Aicardi Syndrome nor is there a standard course of treatment. Treatment generally involves medical management of seizures and programs to help parents and the child cope with developmental delays.
The prognosis for girls with Aicardi Syndrome varies according to the severity of their symptoms. The known age range of affected children is from birth to the mid 20's.
Links on Aicardi Syndrome
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- Aicardi Syndrome Foundation
- Aicardi Syndrome medical information: This site provides information on definintion, causes, treatment, and much more.
- Aicardi symptom summary list: This page provides a summary, list of synonyms, and the major features.
- Aicardi Syndrome and inheritance problems: General information, including associated conditions, plus inheritance patterns.
- Aicardi Syndrome awareness and support group and newsletter informtion
- Statistics on Aicardi Syndrome
- Statistics by country on Aicardi Syndrome
- Associated conditions of Aicardi syndrome
- First hand article on Aicardi Syndrome and a second grade girl : For those of you who don't know my daughter Hannah very well, she is considered severly delayed in all areas. That phrase, however, sounds worse than it actually is. There are lots of things Hannah can do. They just aren't the kinds of skills people use to measure success. Read and see more. This article includes pictures
- United Leukodystrophy Foundation: A wealth of informtion on these diseases including Aicardi Syndrome.